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Monoclonal mouse anti-respiratory syncytial virus (RSV), in vitro Cat.#

3ReS21cc

Data Sheet

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Properties
Unit

mg

Cat.#

3ReS21cc

MAbs:

9C5cc, 8B10cc

Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunised with purified RSV, strain Long.

Specificity:

F protein for MAb 9C5cc
N protein for MAb 8B10cc

MAb 9C5cc is highly reactive with the surface domains of both mature RSV virions and "empty" virion envelopes without formed inner nucleocapsid structures.
MAb 8B10cc is reacting well only with mature virions with completely assembled nucleocapsids. It is failing to recognize the N-protein epitope of immature and destroyed virions, which indicates on conformation dependence of the MAb 8B10cc binding site.

MAb isotypes:

IgG2a for MAb 8B10cc
IgG2b
for MAb 9C5cc

Purification:

Chromatography on protein A Sepharose

Presentation:

PBS, pH 7.4, 0.09 % sodium azide (NaN)

Storage:

+4 °C (+2 … +8 °C allowed)

Material safety note:

This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.

Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Additional product information:

Influenza and other Acute Respiratory Diseases (ARDs) TechNotes
Antibodies Produced in vitro

References:

See all references.
Search other references from PubMed.

Related products:

Cat# 8RSV79: Respiratory Syncytial Virus

Download datasheet as a PDF file below