Respiratory syncytial virus (RSV), antibody

Cat.# 3ReS21 / 3ReS21cc

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Infectious diseases
  • Cat.#

    3ReS21 / 3ReS21cc

  • MABs in vitro (Cat.# 3ReS21cc) :

    9C5cc

     

  • MABs in vivo (Cat.# 3ReS21) :

    8B10

    Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunised with purified RSV, strain Long.

  • Specificity:

    9C5cc: F protein, highly reactive with the surface domains of both mature RSV virions and "empty" virion envelopes without formed inner nucleocapsid structures.8B10: Nucleoprotein (N), reacts well only with mature virions with completely assembled nucleocapsids.

    MAb 8B10 is failing to recognize the N-protein epitope of immature and destroyed virions, which indicates on conformation dependence of the MAb 8B10 binding site.

     

  • MAb isotypes:

    IgG2a for 8B10

    IgG2b for 9C5cc

  • Applications:

     

    MAb are working in ELISA and in lateral flow.

    MAb 8B10 can be used for detection of incomplete virus assembly.

     

  • Purification:

    Protein A chromatography for 9C5cc

    Protein B chromatography for 8B10

  • Presentation:

    PBS, pH 7.4, 0.09 % sodium azide (NaN₃)

  • Storage:

    +4 °C (+2 … +8 °C allowed)

  • Material safety note:

    This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.

    Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

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Respiratory syncytial virus (RSV), antibody (MAb: )

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Respiratory syncytial virus (RSV), antibody (MAb: )

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