3ReS21 / 3ReS21cc
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunised with purified RSV, strain Long.
9C5cc: F protein, highly reactive with the surface domains of both mature RSV virions and "empty" virion envelopes without formed inner nucleocapsid structures.8B10: Nucleoprotein (N), reacts well only with mature virions with completely assembled nucleocapsids.
MAb 8B10 is failing to recognize the N-protein epitope of immature and destroyed virions, which indicates on conformation dependence of the MAb 8B10 binding site.
IgG2a for 8B10
IgG2b for 9C5cc
MAb are working in ELISA and in lateral flow.
MAb 8B10 can be used for detection of incomplete virus assembly.
Protein A chromatography for 9C5cc
Protein B chromatography for 8B10
PBS, pH 7.4, 0.09 % sodium azide (NaN₃)
+4 °C (+2 … +8 °C allowed)
This product is sold for research or further manufacturing use only. Standard Laboratory Practices should be followed when handling this material.
Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
(Catalogue number and MAb: 3ReS21 / 3ReS21cc-)