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PAPP-A, heterotetrameric form (htPAPP-A) Cat.#

8P64

Data Sheet

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Properties
Cat.#

8P64

Source:

Pooled human retroplacental blood.

Material was tested and found negative for HBsAg, HCV, HIV-1and 2 antibodies, HCV antibodies, and syphilis.

Composition:

Heterotetrameric complex, consisting of PAPP-A and pro-MBP subunits (PAPP-A/proMBP complex).

Applications:

Calibrator or standard for htPAPP-A or dPAPP-A assays. PAPP-A can be used for in vitro testing of Down syndrome and other fetal disorders.

Analysis:

Purity > 85 % (SDS-PAGE)

Immunological activity:

Immunological activity has been tested with monoclonal antibodies specific to PAPP-A.

Purification:

Ion-exchange chromatography, affinity chromatography, gel-filtration and negative immunoaffinity chromatography.

Presentation:

Lyophilized from solution in 10 mM Tris-HCl, 0.15 M NaCl, pH 7.5.

It is recommended to reconstitute this product with deionized water to its initial concentration.

Storage:

Lyophilized -20°C (-15 … -30 °C allowed)
Reconstituted -70°C (-65 … -80 °C allowed)

Material safety note:

This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.

Additional product information:

Pregnancy Associated Plasma Protein A (PAPP-A) TechNotes

References:

See other cardiac markers and blood coagulation products.
See other fertility products.
See all PAPPA-A References.
Search other references from PubMed.

Download datasheet as a PDF file below