PAPP-A, heterotetrameric form (htPAPP-A)

Cat.# 8P64

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Fertility and pregnancy
  • Cat.#

    8P64

  • Source:

    Pooled human retroplacental blood.

    Material was tested and found negative for HBsAg, HCV, HIV-1 and 2 antibodies, HCV antibodies, and syphilis.

  • Composition:

    Heterotetrameric complex, consisting of PAPP-A and pro-MBP subunits (PAPP-A/proMBP complex).

  • Applications:

    Calibrator or standard for htPAPP-A or dPAPP-A assays. PAPP-A can be used for in vitro testing of Down syndrome and other fetal disorders.

  • Analysis:

    Purity > 85 % (SDS-PAGE)

  • Immunological activity:

    Immunological activity has been tested with monoclonal antibodies specific to PAPP-A.

  • Purification:

    Ion-exchange chromatography, affinity chromatography, gel-filtration and negative immunoaffinity chromatography.

  • Presentation:

    Lyophilized from solution in 10 mM Tris-HCl, 0.15 M NaCl, pH 7.5.

    It is recommended to reconstitute this product with deionized water to its initial concentration.

  • Storage:

    Lyophilized -20°C (-15 … -30 °C allowed)
    Reconstituted -70°C (-65 … -80 °C allowed)

  • Material safety note:

    This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.

  • Additional product information:
  • References:

    See other cardiac markers and blood coagulation products.
    See other fertility products.
    See all PAPPA-A References.
    Search other references from PubMed.

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PAPP-A, heterotetrameric form (htPAPP-A) (MAb: )

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