Thyroglobulin, in vitro, antibody

2TG12cc

G51, TG61, TG64, TG66
Recombinant chimeric antibody expressed in a mammalian cell line. Composed of original wild type 
variable domains of rat derived MAb and human IgG1 constant domains.

TG12 
Recombinant monoclonal antibody expressed in a mammalian cell line. Full-size IgG sequence 
derived from rabbit B cells

TG08, TG14, TG16, TG23, TG36, TG37, TG46, TG47, 5E6cc, 5F9cc
Mouse monoclonal antibody produced in bioreactor. Hybridoma clone derived from hybridization of
Sp2/0 myeloma cells with spleen cells of Balb/c mice.

Thyroglobulin from human thyroid gland

Human thyroglobulin. 
TG12, TG14, TG16, TG23, TG36, TG37, TG46, TG47, TG64, 5E6cc, 5F9cc exhibit no or low 
interference with thyroglobulin autoantibodies.
TG08, TG51, TG61, TG66 compete with thyroglobulin autoantibodies (exhibit high interference).
5F9cc cross-reacts with bovine thyroglobulin

gG for TG12
IgG1 for TG08, TG14, TG16, TG23, TG36, TG37, TG47, TG51, TG61, TG64, TG66
IgG2a for TG46, 5F9cc
IgG2b for 5E6cc

Detection of human thyroglobulin in immunoassays. 
Recommended pairs for sandwich immunoassay:

TG08, TG51, and TG61 are intended for developing immunoassays for the quantitative determination 
of thyroglobulin autoantibodies, as these MAbs target thyroglobulin epitopes recognized by 
autoantibodies. TG08, TG51, or TG61 can be used individually in competitive immunoassays. In 
addition, TG08 or TG61 can be combined with the supplemental antibody TG66 in competitive 
formats; the recommended primary-to-supplemental antibody ratio is 3:1.
MAbs TG08, TG12, TG14, TG16, TG23, TG36, TG37, TG46, TG47, TG51, TG61, TG64, 5E6cc and
5F9cc work in Western blotting.

Protein A chromatography

0 mM sodium citrate, 150 mM NaCl, pH 6.0, 0.09 % sodium azide (NaN3) for TG36, TG37, 
TG46, TG47
PBS, pH 7.4, 0.09 % sodium azide (NaN3) for TG08, TG12, TG14, TG16, TG23, TG51, TG61, 
TG64, TG66, 5E6cc, 5F9cc

+4 °C (+2 … +8 °C allowed)

This product is sold for research or further manufacturing use only. Standard Laboratory Practices should be followed when handling this material.

Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.