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Monoclonal mouse anti-human dimeric form of pregnancy-associated plasma protein A (dPAPP-A) Cat.#

4PD4

Data Sheet

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Properties
Unit

mg

Cat.#

4PD4

MAbs:

PAPP2, PAPP30

Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified human atherosclerotic tissue form of PAPP-A.

Specificity:

Human recombinant PAPP-A and human endogenous PAPP-A from atherosclerotic tissue (dimeric form of PAPP-A). No cross-reactivity with human heterotetrameric complex of PAPP-A (PAPP-A/ proMBP).

MAb isotypes:

IgG1 for all MAbs

Applications:

dPAPP-A immunoassays and immunoprecipitation.

Recommended pairs for specific detection of dPAPP-A antigen (capture - detection):

PAPP52 (Cat.# 4P41) – PAPP30
PAPP2 – 7A6 (Cat.# 4P41)

Please see Cat.# 4P41 Data Sheet for recommended pairs for detection of human htPAPP-A antigen
and total PAPP-A (htPAPP-A and/or dPAPP-A).

Selective dPAPP-A immunodetection in Western blotting. MAb PAPP2 recognizes dPAPP-A in nonreducing conditions. No cross-reaction with human heterotetrameric complex of PAPP-A (PAPPA/proMBP) was shown for this MAb in WB.

Purification:

Chromatography on protein A Sepharose.

Presentation:

PBS, pH 7.4, 0.09 % sodium azide (NaN)

Storage:

+4 °C (+2 … +8 °C allowed)

Material safety note:

This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.

Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Additional product information:

Pregnancy Associated Plasma Protein A (PAPP-A) TechNotes

References:

See other cardiac markers and blood coagulation products.
See all PAPP-A References.
Search PAPP-A references from ᅠPubMedᅠ.

Download datasheet as a PDF file below